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Product name:MK-0364
CAS:701977-09-5
Molecular Formula:C27H25ClF3N3O2
Formula Weight:515.95g/mol
Description:MK-0364 was shown to be a highly potent CB1R inverse agonist that inhibited the binding and functional activity of various agonists with a binding Ki of 0.13 nM for the human CB1R in vitro.It was sufficient to reduce body weight. The magnitude of weight loss was correlated with brain CB1R occupancy.
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