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4-Amino-2-(1-methylsulfonylpiperidin-4-yl)amino pyrimidin-5-yl(2,3-difluoro-6-methoxyphenyl)methanone

Product name:[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone

CAS:741713-40-6

Molecular Formula:C18H21F2N5O4S

Formula Weight:441.45g/mol

Description:It is a potent and highly selective ATP-competitive inhibitor of the CDKs. In vitro, R547 inhibited the proliferation of tumor cell lines and was active in all 19 cell lines tested irrespective of tissue of origin, multidrug resistance (MDR), p53, or retinoblastoma status.

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