Product name:Nigericin
CAS:28380-24-7
Molecular Formula:C40H67NaO11
Formula Weight:746.94g/mol
Description:Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the 1950s but in 1968 the structure could be elucidated by X-ray crystallography. The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct, or contaminant, at the fermentation of Geldanamycin.In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions. Nigericin exhibits anti-HIV activity.