Agomelatine

by:Acridine Raw Material,Pharmaceutical Chemicals,Fine Chemicals,Chemicals
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Product name:Agomelatine

CAS
:138112-76-2

Molecular Formula:C15H17NO2

Formula Weight:243.30098g/mol

Description:Agomelatine is chemical compound that is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression (forced swimming test in rodents). It is concluded that the antidepressant-like activity in this model most probably involves a combination of both its melatonin agonist and 5-HT(2C) receptor antagonist properties.It is comparible to paroxetine in treatment of major depression.

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