Daunorubicin hydrochloride

by:Acridine Raw Material,Pharmaceutical Chemicals,Fine Chemicals,Chemicals
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Product name:Daunorubicin hydrochloride


Molecular Formula:C27H30ClNO10

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:Daunorubicin Hydrochloride, an antimitotic, antitumor and cytotoxic anthracycline antibiotic derived from the strain of Streptomyces coeruleorubidus, intercalates between base pairs to form complexes with DNA. It maintains the stability of DNA-topoisomerase II complex which prevents topoisomerase II from catalyzing the religation part of the ligation-religation reaction leading to single and double strand DNA breaks. It also blocks polymerase activity, affects regulation of gene expression and produces free radical damage to DNA.Daunorubicin Hydrochloride is used with other antineoplastics to induce remissions in acute leukaemias.

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